• Jianpeng Xiao Jianpeng Xiao
  • Ji Peng Ji Peng
  • Yonghui Zhang Yonghui Zhang
  • Tao Liu Tao Liu
  • Shannon Rutherford Shannon Rutherford
  • Hualiang Lin Hualiang Lin
  • Zhengmin Qian Zhengmin Qian
  • Cunrui Huang Cunrui Huang
  • Yuan Luo Yuan Luo
  • Weilin Zeng Weilin Zeng
  • Cordia Chu Cordia Chu
  • Wenjun Ma Wenjun Ma

Although several studies have documented that latitude might be an effect modifier of the association between temperature and mortality, little is known about how much latitude modifies the temperature-mortality relationship. In this study, we examined this research question using a distributed lag non-linear model and meta-regression alysis based on data from 13 large cities of eastern US from the US tiol Morbidity, Mortality, and Air Pollution Study. We found that cold effects lasted about 1 month while hot effects were acute and short-term. Meta-regression alysis showed that latitude modified both the cold and hot effects with statistical significance. The cold effect decreased with the latitude increment, with -0.11 % change of mortality effect for 1ࠩncrement, while the hot effect increased with the latitude increment, with 0.18 % change of mortality effect for 1ࠩncrement. This finding indicates the importance of latitude on temperature-related mortality risk, which is helpful for city to develop localized effective adaptation strategy in the context of climate change.