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Overview

Current Work

I have an international reputation in viral immunology, focussing on virus-host relationships, with the aim of developing new therapies. I am internationally recognised for my arbovirus work. The core research activities in my laboratory are in-depth investigations of viral diseases, their pathogenesis, treatment and prevention and virus-host interactions, including the role of soluble mediators, cell subsets and viral factors in virus-induced disease. My laboratory has a major focus on commercial translation with recent patents and licenses:

i. Recent work from my lab (with Dr Lara Herrero) showing that pentosan can protect against cartilage damage has led to licensing of that discovery to an Australian biotech company (Paradigm BioPharmaceuticals).

ii. We have developed new antivirals against dengue virus. Biotron Ltd has taken exclusive license to IP on our antiviral agents for dengue virus.

iii. We (with Dr Adam Taylor) have recently developed and patented a vaccine candidate for chikungunya virus.

iv. We have developed a vaccine for Zika virus, preclinical testing are presently underway.
 

News

Expertise Keywords

  • Antiinflammatory drugs
  • Antiviral drugs
  • Chikungunya virus
  • Dengue virus
  • Emerging viruses
  • Human metapneumovirus
  • Immunology
  • Inflammation
  • Mosquito borne viruses
  • Respiratory syncytial virus
  • Ross River virus
  • Vaccines
  • Zika virus

Subject Area Codes

  • Immunology
  • Infectious Diseases
  • Rheumatology and Arthritis
  • Virology

Country Affiliations

  • Brazil
  • China
  • Estonia
  • India
  • Singapore
  • United Kingdom
  • United States

Research Publications and Outputs

Recent Publications

Publications: 89 (Other: 89)

Funded Griffith Research

Engagement and Impact

Learning and Teaching

Current and Past Courses

  • Infectious Disease (3012BPS)
    Teacher, In Person, Nathan Campus, Semester 2, 2015.
  • Infectious Disease (3012NSC)
    Teacher, In Person, Nathan Campus, Semester 2, 2015.

Research by Higher Degree Supervision or Scholarship

Supervision Overview

Supervised a number of successful higher degree scholars (10 completed; 8 PhD students have completed in 2004-2016), most of whom have continued with a career in science. Nine of my fifteen Honours students obtained HI (2 University Medalist). Mentored 4 postdoctoral fellows, including a NHMRC CDA2, 4 Peter Doherty, 1 ARC APDI, 1 ARC DECRA and 4 other postdoctoral fellows.

Theses Supervised at Griffith

Background

Bio

I am a viral immunologist, with a particular interest in the pathogenesis and treatment of viral-induced inflammatory diseases. I am presently a NHMRC Senior Research Fellow and Professor and Principal Research Leader at the Institute for Glycomics, Griffith University. Perhaps my greatest achievement has been the large body of work over 10 years identifying mechanisms in alphavirus musculoskeletal disease. My contribution to fundamental research is complemented by clinical and translational ‘spin-offs’ supported by highly productive collaborations with clinician-scientists and commercial partners. He
is actively engaged in commercialization projects to develop anti-inflammatory drugs, antivirals and vaccines through research option agreements with Biotech and Pharma. He has received numerous awards and honours from major Australian funding and research bodies. He was made Fellow of the American Academy of Microbiology for his contributions to the field of virology.
 

Education and Training

  • BScHons Bachelor Of Science With Honours, National University of Malaysia - 1992

Academic experience

  • NHMRC Fellow, Australian National University 2000 - 2002
  • NHMRC Fellow, University of Wollongong 2003 - 2004
  • Professor, University of Canberra 2005 - 2010

Awards and Honours

  • Career Development Award (Level 2), NHMRC 2009 - 2009
  • R. Douglas Wright Fellowship, NHMRC 2004 - 2008
  • ScienceNOW Young scientist, Fresh Science 2001 - 2001
  • NHMRC Peter Doherty Fellowship, NHMRC 2000 - 2003
  • Ann Woolcock Fellowship, Australian Respiratory Council 2000 - 2000
  • PhD Scholarship, Australian National University 1994 - 1998
  • John Crawford International PhD Scholarship, Australian Government 1994 - 1998
  • Postgraduate Research Fellowship, University of Malaya 1993 - 1994
  • One of three finalists - UNSW Eureka Prize for Scientific Research, Australian Museum 2005 - 2005
  • Fellow, American Academy of Microbiology 2016 -
  • Member for Virology, Faculty 1000 2016 -
  • Senior Research Fellowship, NHMRC 2014 -
  • Young Tall Poppy Award, Australian Institute for Policy and Science 2004 - 2004
  • Future Fellowship, ARC 2009 - 2013
  • Undergraduate Scholarship, Malaysian Government 1988 - 1992

Professional experience

  • Grant Review Panel, Department of Industry, Innovation, Climate Change, Science, Research and Tertiary Education 2013 - 2014
  • ACT Convenor, ACT Australian Society for Medical Research (ASMR). 2008 - 2009
  • Biotechnology Advisory Board to the ACT Government (Ausbiotech), ACT Government 2005 - 2010
  • International Advisory Board, EU Runemerge program - Centre for Research and Intelligence on Emerging Diseases in the Indian Ocean 2011 - 2013
  • International PhD Advisor, College of Veterinary Medicine, Sichuan Agricultural University, China 2016 -
  • National Tall Poppy Ambassador, Queensland Tall Poppy Ambassador 2005 - 2010
  • Queensland Tall Poppy Ambassador, Australian Institute for Policy and Science 2011 -
  • Board of Directors, Australian Institute for Policy and Science 2015 -
  • Virology Chair - Special Interest Group, Australian Society for Microbiology 2011 -
  • Deputy Director, Queensland Tropical Health Alliance (QTHA) 2013 - 2015
  • Grant Review Panel (Microbiology/Virology), NHMRC 2011 - 2014
  • Grant Review Panel (Microbiology/Virology), NHMRC 2011 - 2014
  • Grant Review Panel (Inflammation), NHMRC 2007 - 2009
  • Assigners Academy, NHMRC 2015 -

Editorial roles

  • Editorial board member, Microbes and Infection 2007 -
  • Editorial board member, Virus Disease 2013 -
  • Editorial board member, Viral Immunology 2015 -
  • Editorial board member, Virology Journal 2013 - 2015
  • Section Editor, Virology Journal 2015 -
  • Editorial board member, Journal of General Virology 2015 -
  • Editorial board member, Journal of Virology 2016 -

Professional memberships

  • FAAM Fellow, American Academy of Microbiology 2016 -
  • Member, Australian Rheumatology Association 2015 -
  • Member, Australian Virology Society 2005 -
  • Member, American Society for Microbiology 2009 -
  • ACT Convenor, Australian Society for Medical Research 2008 - 2009
  • Member, National Association of Research Fellows (NARF, NHMRC Inc) 2004 -
  • Member, Asia Pacific Society for Medical Virology 2003 -
  • Member, Australian Society for Microbiology 2005 -
  • AusBiotech Member, Australian Biotechnology (AusBiotech) 2005 - 2010
  • TSANZ Member, Thoracic Society of Australia and New Zealand 2000 - 2002
  • Member, American Society for Leukocyte Biology 2002 - 2004
  • Member, Australian Society for Immunology 1995 - 2002

Government representation roles

  • Biotechnology Advisory Board, ACT Government 2005 - 2010