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Contact Danielle Stanisic

Email

d.stanisic@griffith.edu.au

Phone

(07) 555 29433

Campus

G25 3.62, Gold Coast.

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Overview

Current Work

My research involves the pre-clinical and clinical evaluation of malaria vaccine candidates.

Expertise Keywords

• Babesia
• Clinical Trials
• Immunology
• Malaria
• Parasitology
• Vaccines

Subject Area Codes

• Immunology
• Infectious Diseases

Research Publications and Outputs

Recent Publications

Publications: 49 (Other: 49)

• Feng, G., Boyle, M. J., Cross, N. J., Chan, J.-A., Reiling, L., Osier, F. H. A., … Beeson, J. G. (2018). Human Immunization with a Polymorphic Malaria Vaccine Candidate Induced Antibodies to Conserved Epitopes that Promote Functional Antibodies to Multiple Parasite Strains. Journal of Infectious Diseases, 218(1), 35–43.
• Low, L., Stanisic, D., & Good, M. (2018). Exploiting the apicoplast: apicoplast-targeting drugs and malaria vaccine development. Microbes and Infection, 1–7.
• Reiman, J., Kumar, S., Guzmán, I. R., Gnidehou, S., Ito, K., Stanisic, D., … Good, M. (2018). Induction of immunity following vaccination with a chemically attenuated malaria vaccine correlates with persistent antigenic stimulation. Clinical & Translational Immunology, 7(4), e1015–1–e1015–13.
• Stanisic, D., McCarthy, J. S., & Good, M. (2018). Controlled Human Malaria Infection: Applications, Advances, and Challenges. Infection and Immunity, 86(1), e00479–1–e00479–17.
• Cates, J. E., Unger, H. W., Briand, V., Fievet, N., Valea, I., Tinto, H., … al., et. (2017). Malaria, malnutrition, and birthweight: A meta-analysis using individual participant data. PLoS Medicine, 14(8), e1002373–1–e1002373–20.
• Chan, J.-A., Stanisic, D., Duffy, M., Robinson, L. J., Lin, E., Kazura, J. W., … Beeson, J. G. (2017). Patterns of protective associations differ for antibodies to P. falciparum-infected erythrocytes and merozoites in immunity against malaria in children. European Journal of Immunology, 47(12), 2124–2136.
• McLean, A. R. D., Stanisic, D., McGready, R., Chotivanich, K., Clapham, C., Baiwog, F., … Fowkes, F. J. I. (2017). P. falciparum infection and maternofetal antibody transfer in malaria-endemic settings of varying transmission. PLoS One, 12(10), e0186577–1–e0186577–18.
• Raja, A., Stanisic, D., & Good, M. (2017). Chemical attenuation in the development of a whole-organism malaria vaccine. Infection and Immunity, 85(7), e00062–17–1–e00062–17–7.
• Raja, A., Stanisic, D., & Good, M. (2017). Immune Responses to Whole-Organism Blood-Stage Malaria Vaccines. In Malaria: Immune Response to Infection and Vaccination (pp. 197–210).
• Chan, J.-A., Howell, K. B., Langer, C., Maier, A. G., Hasang, W., Rogerson, S., … Beeson, J. G. (2016). A single point in protein trafficking by Plasmodium falciparum determines the expression of major antigens on the surface of infected erythrocytes targeted by human antibodies. Cellular and Molecular Life Sciences, 73(21), 4141–4158.
• De, S. L., Stanisic, D., Breda, K. van, Bellette, B., Harris, I., McCallum, F., … Good, M. (2016). Persistence and immunogenicity of chemically attenuated blood stage Plasmodium falciparum in Aotus monkeys. International Journal for Parasitology, 46(9), 581–591.
• De, S. L., Stanisic, D., Rivera, F., Batzloff, M., Engwerda, C. R., & Good, M. (2016). Plasmodium berghei bio-burden correlates with parasite lactate dehydrogenase: application to murine Plasmodium diagnostics. Malaria Journal, 15, 3–1–3–11.
• Manning, L., Cutts, J., Stanisic, D., Laman, M., Carmagnac, A., Allen, S., … Mueller, I. (2016). A Toll-like receptor-1 variant and its characteristic cellular phenotype is associated with severe malaria in Papua New Guinean children. Genes and Immunity, 17, 52–59.
• Raja, A., Cai, Y., Reiman, J., Gloves, P., Chakravarty, S., McPhun, V., … Good, M. (2016). Chemically Attenuated Blood-Stage Plasmodium yoelii Parasites Induce Long-Lived and Strain-Transcending Protection. Infection and Immunity, 84(8), 2274–2288.
• Stanisic, D., & Good, M. (2016). Examining cellular immune responses to inform development of a blood-stage malaria vaccine. Parasitology, 143(2), 208–223.
• Stanisic, D., Gerrard, J., Fink, J., Griffin, P. M., Liu, X., Sundac, L., … Good, M. (2016). Infectivity of Plasmodium falciparum in Malaria-Naive Individuals Is Related to Knob Expression and Cytoadherence of the Parasite. Infection and Immunity, 84(9), 2689–2696.
• Unger, H. W., Cates, J. E., Gutman, J., Briand, V., Fievet, N., Valea, I., … al., et. (2016). Maternal Malaria and Malnutrition (M3) initiative, a pooled birth cohort of 13 pregnancy studies in Africa and the Western Pacific. BMJ Open, 6, e012697–1–e012697–10.
• Chua, C. L. L., Robinson, L. J., Baiwog, F., Stanisic, D., Hamilton, J. A., Brown, G. V., … Boeuf, P. (2015). High numbers of circulating pigmented polymorphonuclear neutrophils as a prognostic marker for decreased birth weight during malaria in pregnancy. International Journal for Parasitolody, 45, 107–111.
• Reddy, S. B., Anders, R. F., Cross, N., Mueller, I., Senn, N., Stanisic, D., … Persson, K. E. M. (2015). Differences in affinity of monoclonal and naturally acquired polyclonal antibodies against Plasmodium falciparum merozoite antigens. BMC Microbiology, 15, 133–1–133–11.
• Stanisic, D., & Good, M. (2015). Whole organism blood stage vaccines against malaria. Vaccine, 33(52), 7469–7475.
• Stanisic, D., Fowkes, F. J. I., Koinari, M., Javati, S., Lin, E., Kiniboro, B., … Beeson, J. G. (2015). Acquisition of antibodies against Plasmodium falciparum merozoites and malaria immunity in young children and the influence of age, force of infection, and magnitude of response. Infection and Immunity, 83(2), 646–660.
• Stanisic, D., Liu, X., De, S. L., Batzloff, M., Forbes, T., Davis, C., … Good, M. (2015). Development of cultured Plasmodium falciparum blood-stage malaria cell banks for early phase in vivo clinical trial assessment of anti-malaria drugs and vaccines. Malaria Journal, 14, 143–1–143–10.
• Stanisic, D., Moore, K. A., Baiwog, F., Ura, A., Clapham, C., King, C. L., … Rogerson, S. J. (2015). Risk factors for malaria and adverse birth outcomes in a prospective cohort of pregnant women resident in a high malaria transmission area of Papua New Guinea. Transactions of the Royal Society for Tropical Medicine and Hygiene, 109(5), 313–324.
• Finney, O. C., Danziger, S. A., Molina, D. M., Vignali, M., Takagi, A., Ji, M., … Wang, R. (2014). Predicting anti-disease immunity using proteome arrays and sera from children naturally exposed to malaria. Molecular and Cellular Proteomics, 13(10), 2646–2660.
• Stanisic, D., Cutts, J., Eriksson, E., Fowkes, F. J. I., Rosanas-Urgell, A., Siba, P., … Schofield, L. (2014). γδ T cells and CD14+ Monocytes Are Predominant Cellular Sources of Cytokines and Chemokines Associated With Severe Malaria. Journal of Infectious Diseases, 210(2), 295–305.
• Terheggen, U., Drew, D. R., Hodder, A. N., Cross, N. J., Mugyenyi, C. K., Barry, A. E., … Beeson, J. G. (2014). Limited antigenic diversity of Plasmodium falciparum apical membrane antigen 1 supports the development of effective multi-allele vaccines. BMC Medicine, 12, 183–1–183–20.
• Good, M., Reiman, J., Guzmán, I. R., Ito, K., Yanow, S. K., El-Deeb, I. M., … McPhun, V. (2013). Cross-species malaria immunity induced by chemically attenuated parasites. Journal of Clinical Investigation, 123(8), 3353–3362.
• Stanisic, D., & Good, M. (2013). Induction of anti-Plasmodium immunity following subpatent infection with live erythrocytic stages and drug cure. Methods in Molecular Biology, 923, 535–547.
• Stanisic, D., Barry, A. E., & Good, M. (2013). Escaping the immune system: How the malaria parasite makes vaccine development a challenge. Trends in Parasitology, 29(12), 612–622.
• Stanisic, D., Javati, S., Kiniboro, B., Lin, E., Jiang, J., Singh, B., … Mueller, I. (2013). Naturally Acquired Immune Responses to P. vivax Merozoite Surface Protein 3α and Merozoite Surface Protein 9 Are Associated with Reduced Risk of P. vivax Malaria in Young Papua New Guinean Children. PLoS Neglected Tropical Diseases, 7(11), e2498–1–e2498–8.
• Umbers, A. J., Stanisic, D., Ome, M., Wangnapi, R., Hanieh, S., Unger, H. W., … Rogerson, S. J. (2013). Does Malaria Affect Placental Development? Evidence from In Vitro Models. PL o S One, 8(1), e55269–1–e55269–10.
• Beteula, I., Bassat, Q., Kiniboro, B., Robinson, L. J., Rosanas-Urgell, A., Stanisic, D., … Mueller, I. (2012). Tolerability and Safety of Primaquine in Papua New Guinean Children 1 to 10 Years of Age. Antimicrobial agents and Chemotherapy, 56(4), 2146–2149.
• Beteula, I., Rosanas-Urgell, A., Kiniboro, B., Stanisic, D., Samol, L., Lazzari, E., … Mueller, I. (2012). Relapses Contribute Significantly to the Risk of Plasmodium vivax Infection and Disease in Papua New Guinean Children 1–5 Years of Age. Journal of Infectious Diseases, 206(11), 1771–1780.
• Mayor, A., Bardaji, A., Felger, I., King, C., Cistero, P., Dobano, C., … Rogerson, S. (2012). Placental Infection With Plasmodium vivax: A Histopathological and Molecular Study. Journal of Infectious Diseases, 206(12), 1904–1910.
• Rosanas-Urgell, A., Lin, E., Manning, L., Rarau, P., Laman, M., Senn, N., … Mueller, I. (2012). Reduced Risk of Plasmodium vivax Malaria in Papua New Guinean Children with Southeast Asian Ovalocytosis in Two Cohorts and a Case-Control Study. PLoS Medicine, 9(9), e1001305–1–e1001305–11.
• Senn, N., Rarau, P., Stanisic, D., Robinson, L., Barnadas, C., Manong, D., … Mueller, I. (2012). Intermittent Preventive Treatment for Malaria in Papua New Guinean Infants Exposed to Plasmodium falciparum and P. vivax : A Randomized Controlled Trial. Plos Medicine, 9(3), e1001195–1–e1001195–14.
• Manning, L., Laman, M., Stanisic, D., Rosanas-Urgell, A., Bona, C., Teine, D., … Davis, T. M. E. (2011). Plasma Plasmodium falciparum Histidine-Rich Protein-2 Concentrations Do Not Reflect Severity of Malaria in Papua New Guinean Children. Clinical Infectious Diseases, 52(4), 440–446.
• Umbers, A. J., Boeuf, P., Clapham, C., Stanisic, D., Baiwog, F., Mueller, I., … Rogerson, S. J. (2011). Placental Malaria-Associated Inflammation Disturbs the Insulin-like Growth Factor Axis of Fetal Growth Regulation. Journal of Infectious Diseases, 203(4), 561–569.
• Fernandez-Becerra, C., Sanz, S., Brucet, M., Stanisic, D., Alves, F., Camargo, E., … Portillo, H. del. (2010). Naturally-acquired humoral immune responses against the N- and C- termini of the Plasmodium vivax MSP1 protein in endemic regions of Brazil and Papua New Guinea using a multiplex assay. Malaria Journal, 9(1), 1–8.
• Hommel, M., Elliott, S. R., Soma, V., Kelly, G., Fowkes, F. J. I., Chesson, J. M., … Beeson, J. G. (2010). Evaluation of the Antigenic Diversity of Placenta-Binding Plasmodium falciparum Variants and the Antibody Repertoire among Pregnant Women. Infection and Immunity, 78(5), 1963–1978.
• Lin, E., Kiniboro, B., Gray, L., Dobbie, S., Robinson, L., Laumaea, A., … Mueller, I. (2010). Differential Patterns of Infection and Disease with P. falciparum and P. vivax in Young Papua New Guinean Children. PloS One, 5(2), e9047–1–e9047–15.
• Richards, J. S., Stanisic, D., Fowkes, F. J. I., Tavul, L., Dabod, E., Thompson, J. K., … Beeson, J. G. (2010). Association between naturally acquired antibodies to erythrocyte-binding antigens of Plasmodium falciparum and protection from malaria and high-density parasitemia. Clinical Infectious Diseases, 51(8), e50–e60.
• Stanisic, D., Mueller, I., Betuela, I., Siba, P., & Schofield, L. (2010). Robert Koch redux: malaria immunology in Papua New Guinea. Parasite Immunology, 32(8), 623–632.
• Robinson, L. J., D⿿Ombrain, M. C., Stanisic, D., Taraika, J., Bernard, N., Richards, J. S., … Schofield, L. (2009). Cellular Tumor Necrosis Factor, Gamma Interferon, and Interleukin-6 Responses as Correlates of Immunity and Risk of Clinical Plasmodium falciparum Malaria in Children from Papua New Guinea. Infection and Immunity, 77(7), 3033–3043.
• Stanisic, D., Richards, J. S., McCallum, F. J., Michon, P., King, C. L., Schoepflin, S., … Beeson, J. G. (2009). Immunoglobulin G subclass-specific responses against Plasmodium falciparum merozoite antigens are associated with control of parasitemia and protection from symptomatic illness. Infection and Immunity, 77(3), 1165–1174.
• Bartley, P. B., Glanfield, A., Li, Y., Stanisic, D., Duke, M., Jones, M. K., & McManus, D. P. (2008). Artemether Treatment of Prepatent Schistosoma japonicum Induces Resistance to Reinfection in Association with Reduced Pathology. American Journal of Tropical Medicine and Hygiene, 78(6), 929–935.
• D⿿Ombrain, M. C., Robinson, L. J., Stanisic, D., Taraika, J., Bernard, N., Michon, P., … Schofield, L. (2008). Association of early interferon-γ production with immunity to clinical malaria: a longitudinal study among Papua New Guinean children. Clinical Infectious Diseases, 47(11), 1380–1387.
• King, C. L., Michon, P., Shakri, A. R., Marcotty, A., Stanisic, D., Zimmerman, P. A., … Chitnis, C. E. (2008). Naturally acquired Duffy-binding protein-specific binding inhibitory antibodies confer protection from blood-stage Plasmodium vivax infection. Proceedings of the National Academy of Sciences of the United States of America, 105(24), 8363–8368.
• Wykes, M. N., Liu, X. Q., Beattie, L., Stanisic, D., Stacey, K. J., Smyth, M. J., … Good, M. F. (2007). Plasmodium Strain Determines Dendritic Cell Function Essential for Survival from Malaria. PL o S Pathogens, 3(7), 0904–0912.

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Funded Griffith Research

• (2018). Manufacture and evaluation of a chemically attenuated Plasmodium falciparum whole parasite blood-stage malaria vaccine
• (2017). Peptide-based PD-1 Inhibitors and Whole Blood-stage Parasite Malaria Vaccination
• (2014). Development and testing of a chemically attenuated whole parasite malaria vaccine

Engagement and Impact

Learning and Teaching

Research by Higher Degree Supervision or Scholarship

Apply for a PhD or research degree at Griffith

Theses Supervised at Griffith

• 
  Amber Iftikhar Raja (2016) Characterisation of a Chemically Attenuated Blood-Stage Malaria Vaccine for the Rodent Parasite, Plasmodium yoelii Thesis (PhD Doctorate)

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